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Scientific evidence
Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens
Nov 2006
Many uveal melanoma patients die of metastasis despite ocular treatment. Transcriptomic profiling of enucleated tumors can identify patients at high metastatic risk.
Publication: Journal of Molecular Diagnostics
Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
Oct 2004
Melanomas are notoriously difficult to classify because of a lack of discrete clinical and pathological stages. Here, we show that primary uveal melanomas surprisingly cluster into two distinct molecular classes based on gene expression profile.
Publication: Cancer Research