Our test

Your skin cancer care starts with personalized testing

With the results of our DecisionDx-SCC test, you and your doctor can make informed, personalized decisions based on your unique tumor profile.

DecisionDx-SCC: For patients with high-risk SCC

For patients with SCC and one or more high-risk factors, DecisionDx-SCC is the only genomic test proven to predict the risk of metastasis. Here, you can learn about the testing process, what you can expect from test results, hear from patients, see FAQs and more.

How DecisionDx-SCC helps personalize your care

DecisionDx-SCC test identifies the risk of squamous cell tumors spreading, better than traditional risk assessments alone. Test results can be used with established methods, for an even more precise risk prediction. DecisionDx-SCC provides unique insights for squamous cell skin cancer management. Your healthcare provider will use your test results (in combination with other information and procedures) to plan your treatment and ongoing management.

DecisionDx-SCC test result provides a genomic-based determination of your tumor’s likelihood to metastasize within the next three years. The test measures the activity of specific genes in your tumor, providing a result of low (Class 1), higher (Class 2A), or highest (Class 2B) biological risk of metastasis. DecisionDx-SCC provides you and your healthcare provider with an independent classification that is personal to your squamous cell skin cancer.

The test helps personalize your treatment plan. DecisionDx-SCC delivers precision patient classification, complementing commonly used traditional risk factors and improves risk assessment.1

Why choose DecisionDx-SCC genomic testing?

Proven

The only test proven to accurately identify the risk of metastasis for SCC patients with one or more high-risk factors

Population

>30,000 patients have received DecisionDx-SCC results that have helped guide physician decision making

Personalized

The DecisionDx-SCC test delivers results that are specific to an individual's tumor biology, leading to personalized and precise treatment plans

Is the DecisionDx-SCC test right for you?

The DecisionDx-SCC test may be right for you if:

  • You've been recently diagnosed with cutaneous SCC
  • You have been identified as having one or more high-risk factors

Testing process

  • Step 1

    Your healthcare professional orders DecisionDx-SCC

  • step 2

    Castle Biosciences works with your healthcare professional’s laboratory to obtain a tissue sample from your original biopsy

  • step 3

    Our laboratory analyzes your tissue sample with our genomic test

  • step 4

    Test results are sent to your healthcare professional so that your individual results can be discussed and used to determine the next steps in your care

What to expect from the results

DecisionDx-SCC test looks at your specific tumor’s biology and will provide you with one of the class results (right). 

These results provide you with personalized information that can improve your ability to:

  • Understand your personalized disease risk
  • Acknowledge what treatment interventions are appropriate
  • Create a plan of action to best fight back against your SCC cancer
Graphic of a DecisionDx SCC test report