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Case Studies
MyPath Melanoma case studies
The following case studies show examples of ambiguous melanocytic lesions and demostrate how gene expression profile testing can provide guidance for difficult-to-diagnose lesions and improve patient management.
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Alexander Witkowski, MD, PhD
Dermatologist
Director, OHSU Skin Cancer Imaging Center
Assistant Professor of Dermatology, School of Medicine
Portland, Oregon
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Babar K. Rao, MD, FAAD
Professor of Dermatology and Pathology
Rutgers Center for Dermatology
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Cary Chisholm, MD
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Clay Cockerell, MD, MBA, JD
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Hadas Skupsky, MD, FAAD
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Etan Marks, DO
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Barry White, MD
Director of Dermatopathology at PathAI Diagnostics
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Drazen Jukic, MD, PhD
Dermatopathologist and Director at Georgia Dermatopathology
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High-risk melanoma diagnosed and risk-stratified with MyPath Melanoma and DecisionDx-Melanoma
A 74-year-old male with a dome-shaped red papule on right central frontal scalp.
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Inconclusive PRAME staining on high-stakes lesion on face
A 34-year-old male with a positive family history of melanoma presents with a lesion on the right lateral malar cheek. It was questionable if the lesion had been previously biopsied.
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Aberrant PRAME expression in acral nevus
A 70-year-old male presented with a atypical melanocytic proliferation on his right instep. He had no personal or family history of melanoma. The clinical diagnosis was acral nevus - rule out atypia.
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Concerning melanocytic lesion in patient with personal history of melanoma
A 49-year-old male was seen by a dermatologist for a concerning nevus on the right superior lateral neck. The patient's age, extensive solar damage, and history of metastatic melanoma was a cause for concern.
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Abnormally pigmented lesion with uncertain malignant potential
A woman in her 30's presents to her dermatologists for evaluation of a isolated lesion with irregular pigmentation on her inner thigh.
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Atypical melanocytic proliferation on sensitive preauricular cheek
A 65-year-old male presented with an atypical melanocytic proliferation near the left ear. Four sites of basal cell carcinoma and seborrheic keratosis were taken at the same visit.
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Multi-colored lesion with uncertain malignant potential
A 80-year-old male presents to a dermatologist with a multi-colored lesion on his back and a previous history of extensive sun damage and non-melanoma skin cancers.
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Irregular papule with atypical histopathological findings and borderline/unknown diagnosis
A 43-year-old female presents to a dermatologist with a suspicious irregular multi-colored papule on the right dorsal foot.
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Asymmetrical pigmented lesion with high clinical suspicion for melanoma
A 27-year-old female was seen by a primary care physician who recommended follow-up with a dermatologist for assessment of a concerning melanocytic lesion.
